The TSC Alliance® is an internationally recognized nonprofit that does everything it takes to improve the lives of people affected by tuberous sclerosis complex (TSC). We catalyze new treatments, drive research toward a cure and expand access to lifelong support. TSC is a rare genetic disease that causes tumors to grow in different organs, primarily the brain, heart, kidneys, skin, eyes and lungs. Nearly one million people worldwide have TSC. Some live independently with few symptoms while others require more complex care. With the power of families and the support of donors, volunteers, researchers, educators, industry partners and more, we can create a future where everyone affected by TSC can live their fullest lives.

A house-filling favorite in Las Vegas since she opened as one of the hottest tickets in town in June 2000, Rudner is known for her epigrammatic one-liners. Over the course of a multi-year run she sold almost two million tickets, grossed over a hundred million dollars and become the longest-running solo female comedy show in the history of Las Vegas. She was named Las Vegas’s Comedian of The Year nine years in a row and in 2006 received The Nevada Ballet’s Woman Of The Year Award. In October 2017 she was given the Casino Entertainment Legend Award.

Rita’s first solo HBO special, Rita Rudner’s One Night Stand, was nominated for several awards, as was her eponymous English BBC television show that later appeared in the USA on A&E. Rudner’s two one-hour specials for HBO, Born to Be Mild and Married Without Children, were ratings standouts and she performed all over the country, filling Carnegie Hall in New York three times. In 2008 Rita Rudner: Live From Las Vegas was PBS’s first ever stand-up comedy special. Rita Rudner has written six books; her bestselling non-fiction titles, Naked Beneath My Clothes, Rita Rudner’s Guide to Men  and I Still Have It…I Just Can’t Remember Where I Put It, plus the novels Tickled Pink and Turning the Tables.  The audio version of Naked Beneath My Clothes received a Grammy nomination. Her autobiography, My Life in Dog Years, was published earlier this year.

Rudner is a frequent collaborator with her writer/producer husband of thirty years, Martin Bergman. The couple’s first produced film script was Peter’s Friends. The film, starring Emma Thompson, Hugh Laurie, Kenneth Branagh, Imelda Staunton, Stephen Fry, and Rita, won the Evening Standard Peter Sellers Award for Best British Film and was nominated for the Goya Award for Best European Film of 1994. The script was nominated for a WGA Best Screenplay Award and Rita won Best Supporting Actress at the American Comedy Awards.

The couple’s second film project, a TV movie called A Weekend In The Country, starred Rita, Jack Lemmon, Dudley Moore, Richard Lewis, Christine Lahti, Betty White and Faith Ford. Bergman and Rudner’s last film, Thanks, premiered at the 2011 Palm Springs International Film Festival, won several awards on the film festival circuit and was bought by and frequently aired on Showtime. 

In 2003, Rudner launched from Las Vegas her first syndicated daily TV show, Ask Rita, which featured a panel of celebrities lightheartedly attempting to solve personal problems submitted by members of the public; it ran for two years. For her work on the show, American Women In Radio and Television awarded Rudner a Gracie Allen Award for Best Program Host. Rita helped write the 2001 and 2003 Oscar shows with Steve Martin and the 2002 Oscar broadcast with Whoopi Goldberg. 

Rita Rudner moved to New York at the age of fifteen to become a dancer on Broadway. She appeared in several shows, including the original productions of Follies and Mack and Mabel. It was while in Annie on Broadway that she began exploring the comedy clubs of Manhattan. In the early ‘80s, Rudner took a full-time leap from chorus lines to punch lines and was soon a regular guest on both Late Night With David Letterman and The Tonight Show. 

In 2009, Rita, Bette Midler and Sheryl Crow joined forces to perform a fundraiser for President Obama and the Democratic leader of the Senate, Harry Reid.

In 2012, Rita and Martin wrote and performed The Rita Rudner Show for BBC radio in London. Rita also appeared in the Showtime comedy special Rita Rudner and Three Potential Ex-Husbands.

In June 2016 Rita was invited and honored to speak about her career and technique in comedy at Cambridge University, England. In 2017 she was invited by Oprah Winfrey to appear on a cruise to Alaska that Oprah did in partnership with Holland America.

In 2018, Rita’s tenth TV special was released – A Tale Of Two Dresses. 

In September 2018, Rita appeared at the Laguna Playhouse in the new musical comedy Two’s A Crowd. She and Martin have previously collaborated at the Playhouse on two plays which they co-wrote – Room 776 and Tickled Pink – as well as Act 3… written by David Ambrose and Claudia Nellens. Two’s A Crowd was staged off-Broadway in New York in 2019. The couple's latest play - Staged - premiered at the Laguna Playhouse in January 2023.

Since taking a class called “How To Be A Stand-up Comedian,” Wendy Liebman has performed on The Tonight Show with Johnny Carson, Jay Leno, and Jimmy Fallon, and nine times on the Late Show with David Letterman.  In addition, she was the recipient of the American Comedy Award for Best Female Stand-up Comedian.  You may have seen one of her specials on HBO, Showtime ("Taller on TV"), or Comedy Central, or on one of her appearances on Season 9 of America’s Got Talent. She lives in LA with her husband and two rescued Jindo dogs who are as trainable as a carrot. 

Craig Shoemaker has spent over four decades proving that laughter is more than entertainment, it’s medicine. 

As a stand-up, Craig is best known for his iconic character The Lovemaster and for his comedy specials, including his Comedy Central special ranked in the Top 25 of all time. He’s earned two Emmy Awards, the American Comedy Award for “Best Male Stand-Up Comedian,” and has performed on every major network and streaming platform. He’s appeared in over 200 TV shows and films, with memorable roles on Parks and Recreation, Matlock, and even a cameo in Scream 2. 

Beyond the stage and screen, Craig has built an entirely new lane for himself as a leader in wellness and transformation. He is the founder of Laughter Worx, a corporate training company using his proprietary, non-comedic laughter techniques to shift workplace culture; creator of Laugh Bath™, an immersive laughter-healing experience now rolling out nationwide; and the visionary behind LaffApp, a wellness app blending neuroscience and humor.

He also teaches Command the Room, a masterclass and coaching platform that helps people of all backgrounds (from executives to entertainers) harness humor to elevate presence, storytelling, and connection. Whether you want to crush a keynote, win a sales pitch, or just be the funniest one at the dinner table, Craig has coached thousands on how to use laughter as their ultimate superpower. 

Craig’s career reflects his core belief: that humor is the shortest distance between two people. From Fortune 500 retreats and TED Talks to Hollywood soundstages and television and films, his mission is the same: to heal, inspire, and connect people through the transformative power of laughter.

Mo was born Maureen Anne Collins and raised in Minneapolis, Minnesota, where she started her improv and sketch career with Dudley Riggs BNW in Minneapolis. In 1998 she moved to Los Angeles, where she landed "MadTV", giving birth to many unforgettable characters, such as Lorraine, Stuart's Mother, and Trina. She has since built up her credits with hit shows such as "Arrested Development", "Curb Your Enthusiasm", and "Parks and Recreation" as scandal-wrangler Joan Callamezzo; and in "40-Year-Old Virgin" as Gyna, and seasons 4-7 of "Fear the Walking Dead" as Sarah Rabinowitz. She is a woman of many voice in animation, notably on Netflix's "F is For Family," for which she earned her first Emmy nomination in 2017. Mo is married to actor Alex Skuby and has one son. She enjoys doing stand-up/improvisation and is an avid animal advocate.

Priya Mehta is a creative producer, comedian, and event host who builds experiences that merge entertainment, culture, and connection. She’s produced and hosted some of the most dynamic multicultural comedy and entertainment shows in LA, selling out venues like Laugh Factory, HaHa Comedy Club, The Bourbon Room, and Kookaburra Lounge. She recently opened for acclaimed comedians Zarna Garg, Nimesh Patel, and Akaash Singh and is passionate about representing South Asian voices in comedy and storytelling. Priya uses her platform to celebrate identity and the power of laughter to bring communities together.